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Review Article| Volume 25, P103-125, 2007

Should Nonanesthesia Providers Be Administering Propofol?

      Most patients who undergo invasive procedures require some amount of sedation and analgesia. The American Society of Anesthesiologists (ASA) describes sedation and analgesia along a continuum of states according to the degree of purposeful movement in response to increasing levels of stimulation (Table 1) [
      • American Society of Anesthesiologists
      Practice guidelines for sedation and analgesia by nonanesthesiologists.
      ].
      Table 1Continuum of depth of sedation: definition of general anesthesia and levels of sedation/analgesia
      Minimal sedation (anxiolysis) Moderate sedation/analgesia (conscious sedation) Deep sedation/analgesia General anesthesia
      Responsiveness Normal response to verbal stimulation Purposeful response to verbal or tactile stimulation Purposeful response after repeated or painful stimulation Unarousable, even with painful stimulus
      Airway Unaffected No intervention required Intervention may be required Intervention often required
      Spontaneous ventilation Unaffected Adequate May be inadequate Frequently inadequate
      Cardiovascular function Unaffected Usually maintained Usually maintained May be impaired
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